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Jelly Beans OR Glucose Drink?

Updated: Apr 6, 2024

What types of glucose tolerance tests are there?


There are two types of glucose tolerance tests: a short version called the glucose challenge test, and a full glucose tolerance test. The short version is easier to do and serves as a preliminary test to determine someone's risk of diabetes or gestational diabetes.




Glucose challenge test


The glucose challenge test is the short version of the glucose tolerance test. The test can be done at any time of the day. It involves drinking a glass of concentrated glucose solution (50 g of glucose dissolved in 250 to 300 ml of water). After one hour has passed, a blood sample is taken to determine the blood sugar level.


Glucose tolerance test


For this test, you should not eat anything before going to the doctor in the morning. In other words, you should not have breakfast, and you should eat your last meal the evening before. This also applies to all drinks with the exception of water.


First of all, blood is taken to determine your baseline blood sugar level. The blood is drawn from a vein or your fingertip or earlobe. After that you drink a large glass of concentrated sugar solution. In the glucose tolerance test, 75 g of glucose are dissolved in 250 to 300 ml of water...When testing for gestational diabetes, blood is drawn twice – first after one hour and then again after another two hours.


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Most pregnant women have a glucose screening test between 24 and 28 weeks of pregnancy. The test may be done earlier if you have a high glucose level in your urine during your routine prenatal visits, or if you have a high risk for diabetes. Women who have a low risk for diabetes may not have the screening test.


TWO-STEP TESTING


Abnormal blood values for a 3-hour 100-gram oral glucose tolerance test are:

  • Fasting: greater than 95 mg/dL (5.3 mmol/L)

  • 1 hour: greater than 180 mg/dL (10.0 mmol/L)

  • 2 hour: greater than 155 mg/dL (8.6 mmol/L)

  • 3 hour: greater than 140 mg/dL (7.8 mmol/L)

ONE-STEP TESTING


Abnormal blood values for a 2-hour 75-gram oral glucose tolerance test are:

  • Fasting: greater than 92 mg/dL (5.1 mmol/L)

  • 1 hour: greater than 180 mg/dL (10.0 mmol/L)

  • 2 hour: greater than 153 mg/dL (8.5 mmol/L)

If only one of your blood glucose results in the oral glucose tolerance test is higher than normal, your provider may simply suggest you change some of the foods you eat. Then, your provider may test you again after you have changed your diet.


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This study tested the hypothesis that a standardized dose of jelly beans could be used as an alternative sugar source to the 50-g glucose beverage to screen for gestational diabetes mellitus. Study Design: One hundred sixty pregnant women at 24 to 28 weeks’ gestation were recruited for a prospective study to compare 2 sugar sources for serum glucose response, side effects, preference, and ability to detect gestational diabetes mellitus. Patients were randomly assigned to consume 50-g glucose beverage or 28 jelly beans (50 g simple carbohydrate). Serum glucose values were determined 1 hour later. The test was later repeated with the other sugar source. Finally, a 100-g 3-hour oral glucose tolerance test was performed.


*ASK YOUR OBGYN OR MIDWIFE IF YOU CAN USE 28 JELLYBEANS INSTEAD


Participants completed a questionnaire recording subjective outcome variables. American Diabetes Association criteria were used to interpret all test results. Results: Among 136 participants completing the study no significant differences were found between 1-hour serum glucose values (116.5 ± 27 mg/dL with 50-g glucose beverage, 116.9 ± 23.6 mg/dL with jelly beans; P = .84), frequency of discrepant results (P = .47), sensitivity, specificity, or predictive value. Jelly beans yielded fewer side effects (38% with 50-g glucose beverage, 20% with jelly beans; P <.001) and were preferred by 76% of participants (P < .001). Five cases (3.7% incidence) of gestational diabetes mellitus were diagnosed, 3 with 50-g glucose beverage alone, 1 with jelly beans alone, and 1 with both sugar sources. Conclusions: Jelly beans may be used as an alternative to the 50-g glucose beverage as a sugar source for gestational diabetes mellitus screening. The 2 sources provoke similar serum glucose responses. Patients report fewer side effects after a jelly bean challenge than after a 50-g glucose beverage challenge. (Am J Obstet Gynecol 1999;181:1154-7.)


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content is for informational and educational purposes and does not constitute medical advice

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